2015, Vol. 2 Issue 3, Part B
Insilico assessment of antiviral and antibacterial activity of some selected flavonoids against Bombyx mori
Author(s): Damayanthi Devi. I
Abstract: Flavonoids are a group of polyphenolic compounds distributed ubiquitously among many plants and have been reported to possess antimicrobial activity against a wide range of pathogens. Silkworm Bombyx mori is an important economic insect as it is used to convert leaf protein into silk whose production has an economic importance all over the world. However silkworm mortality is mainly caused by pathogenic microorganisms virus Bombyx mori nuclear polyhedrosis virus and bacteria Staphylococcus aureus thereby reducing the production of silk. In the current study, antibacterial and antiviral activity of the four flavonoids scandenone, tiliroside, quercetin-3,7-O-α-l-dirhamnoside, and kaempferol-3,7-O-α-l-dirhamnoside were studied using insilico techniques. Docking procedures were carried out using GOLD software and the results indicated that the flavonoids scandenone and quercetin-3,7-O-α-l-dirhamnoside possess good antimicrobial activity and could be promising leads for further drug development.
Pages: 86-91 | 702 Views 9 Downloads
How to cite this article:
Damayanthi Devi. I. Insilico assessment of antiviral and antibacterial activity of some selected flavonoids against Bombyx mori. International Journal of Fauna and Biological Studies. 2015; 2(3): 86-91.