International Journal of Fauna and Biological Studies
2015, Vol. 2 Issue 3, Part B
Insilico assessment of antiviral and antibacterial activity of some selected flavonoids against Bombyx mori
Damayanthi Devi. I
Flavonoids are a group of polyphenolic compounds distributed ubiquitously among many plants and have been reported to possess antimicrobial activity against a wide range of pathogens. Silkworm Bombyx mori
is an important economic insect as it is used to convert leaf protein into silk whose production has an economic importance all over the world. However silkworm mortality is mainly caused by pathogenic microorganisms virus Bombyx mori nuclear polyhedrosis virus
and bacteria Staphylococcus aureus
thereby reducing the production of silk. In the current study, antibacterial and antiviral activity of the four flavonoids scandenone, tiliroside, quercetin-3,7-O-Î±-l-dirhamnoside, and kaempferol-3,7-O-Î±-l-dirhamnoside were studied using insilico techniques. Docking procedures were carried out using GOLD software and the results indicated that the flavonoids scandenone and quercetin-3,7-O-Î±-l-dirhamnoside possess good antimicrobial activity and could be promising leads for further drug development.
Pages: 86-91 | 909 Views 14 Downloads
Damayanthi Devi. I. Insilico assessment of antiviral and antibacterial activity of some selected flavonoids against Bombyx mori. Int. J. Fauna Biol. Stud. 2015;2(3):86-91.