Nusrat Rafi and Dr. Rajesh Singh

The second leading cause of death in women is breast cancer; a pattern that is expressed worldwide). While early diagnosis and treatment decrease breast cancer mortality, survival and therapeutic options decrease markedly once the cancer is spreading beyond the breast. Triple negative cancer of the breast (TNBC) is a highly aggressive disease with less treatment options because of the lack of estrogens (ERs), progesterone’s (PRs) and Her2 receptors. The outcome of the present study benefits in identifying the molecular mechanism behind the role of twist protein in breast cancer progression.

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