Author(s):

NI Wayan Sudatri, Nyoman Wirasiti, NI Made Suartini and I Gusti Nyoman Gde Bidura

Abstract: Kaempferia galangal is an herb commonly used as a kitchen spice, herbal medicine for maintaning vitility, body detox, diarrhea medication, treat arthritis, cough medicine, influenza medicine, etc. The purpose of this study was investigate role of anti- diabetic and anti-cholesterol activity of Kaempferia galanga herbal medicine rhizome on albino rats. The design used in this study was Completely Randomized Design with the treatment of different dose of Kaempferia galanga herbal medicine rhizome namely: P0 (Control/without Kaempferia galanga herbal medicine), P1 (dose of 150 mg/kg body weight Kaempferia galanga herbal medicine), P2 (dose of 200 mg/kg BW Kaempferia galanga herbal medicine), P3 (dose of 2500 mg/kg BW Kaempferia galanga herbal medicine), and P4 (dose of 300 mg/kg BW Kaempferia galanga herbal medicine), repectively.Treatment of Kaempferia galanga herbal medicine is done by gavage method everyday for 30 days. The parameters observed were glucose and rat blood cholesterol levels before and after Kaempferia galanga herbal medicine rhizome treatment. The results showed that rat glucose levels before treatment was non significant differences (P>0.05), and after Kaempferia galanga rhizome herbal medicine treatment between control and treatment showed significant differences (P<0.05). Cholesterol levels of Kaempferia galanga rhizome herbal medicine treatment were non significantly different (P>0.05) between control and treatment rats. It was conculded that Kaempferia galanga rhizome herbal medicine has potential as anti-diabetic medicine on certain doses, but not potential as anti-cholesterol medicine.

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