Singita Guha and Srimanti Sarkar

Aim: To determine the indications for Anti-VEGF injection use and the outcomes of the most common pathology in a tertiary eye care centre.
Methodology: This retrospective study analyzed 124 patients from the ASG Eye Hospital in Agarpara. Participants were selected based on specific inclusion and exclusion criteria, with 44 chosen for the DME condition. Central macular thickness (CMT) and visual acuity outcomes were evaluated in these participants before and after a single Accentrix anti-VEGF injection.
Results: Using paired t-test analysis, it was found that among 36 patients administered with one Accentrix injection, there was a statistically significant difference between pre- and post-injection visual acuity and CMT measurements. Diabetic macular edema (DME) emerged as the most prevalent indication for anti-VEGF injection among other ocular pathologies.
Conclusion: Despite various limitations, anti-VEGF therapy has become the new standard of care for treating many ocular pathologies, including diabetic macular edema (DME), due to its effectiveness in enhancing anatomic and visual outcomes. Future research should aim for more detailed examinations, diagnostic procedures, and larger population studies for more accurate results.
 

DOI: 10.22271/23940522.2024.v11.i6a.1055

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