2019, Vol. 6 Issue 5, Part A
Effect of broad range doses of oral administration of Zinc Oxide Nanoparticles in freshwater fish Oreochromis mossambicus
Author(s): Krishnamoorthy Sivakumar, Periyaswamy Subramanian and Ghanshyam N Jha
Abstract: Due to high production and application, nanoproducts reaching aquatic environments have become unavoidable. Among aquatic species, fishes are more susceptible to waterborne contamination and are recognized as bioindicators for water quality monitoring. The present study is to evaluate the haematological and biochemical changes including enzymatic defence systems in freshwater tilapia (Oreochromis mossambicus), on exposure to Zinc Oxide (ZnO) nanoparticles (NP) orally in the range of 100, 200, 300, 400 and 500 ppm for 4 days. ZnO NP led to significant (P<0.05) changes in haematological parameters of Red blood cell (RBC) count, White blood cell (WBC) count, haemoglobin (Hb) concentration and haematocrit with the increasing concentration. Oxidative status of fish was evaluated by analyzing the level of Catalase, Glutathione S-transferase, Superoxide dismutase, Lipid Peroxidase and Reduced Glutathione levels in fish tissues like gill, liver and muscle. ZnO NPs has caused variable changes in oxidative status of O. mossambicus (P<0.05) in a dose dependent manner particularly at 100, 200 and 300 ppm. The study indicates defensive nature and adaptive mechanism of cells against free radical induced toxicity. This study confirms that it will be used to assess the potential health effects of chemicals and products.
Pages: 62-69 | 95 Views 5 Downloads
How to cite this article:
Krishnamoorthy Sivakumar, Periyaswamy Subramanian, Ghanshyam N Jha. Effect of broad range doses of oral administration of Zinc Oxide Nanoparticles in freshwater fish Oreochromis mossambicus. Int J Fauna Biol Stud 2019;6(5):62-69.